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Open-Source MCP servers

Production-ready MCP servers that extend AI capabilities through file access, database connections, API integrations, and other contextual services.

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12,146 servers. Last updated 2025-12-04 15:11
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Matching MCP servers:

  • BioContextAI Knowledgebase MCPofficial

    biocontext-ai
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    An MCP server that provides standardized access to biomedical knowledge bases and resources, enabling AI systems to retrieve verified information from sources like bioRxiv, EuropePMC, and various protein/gene databases.
    Last updated 14 days ago
    52
    16
    Apache 2.0
    • Apple
    • Linux

  • Noctua MCP Serverofficial

    geneontology
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    security
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    license
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    Enables editing and querying of Gene Ontology Causal Activity Models (GO-CAMs) through the Barista API. Supports model creation, individual and fact management, evidence addition, and causal pathway construction for biological knowledge representation.
    Last updated a month ago
    18
    BSD 3-Clause

  • UniProt MCP Server

    josefdc
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    Provides seamless access to UniProtKB protein database, enabling queries for protein entries, sequences, Gene Ontology annotations, full-text search, and ID mapping across 200+ database types.
    Last updated a month ago
    5
    2
    MIT License

  • Biomart MCP

    jzinno
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    A Model Context Protocol server that interfaces with Biomart databases, allowing models to discover biological datasets, explore attributes/filters, retrieve biological data, and translate between different biological identifiers.
    Last updated 6 months ago
    8
    6
    MIT License
    • Apple
    • Linux

  • PubMed MCP Server

    cyanheads
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    A bridge connecting AI agents to NCBI's PubMed database through the Model Context Protocol, enabling seamless searching, retrieval, and analysis of biomedical literature and data.
    Last updated 2 months ago
    5
    145
    36
    Apache 2.0

  • BioMCP

    genomoncology
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    security
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    Provides LLMs with structured access to critical biomedical databases including PubTator3 (PubMed/PMC), ClinicalTrials.gov, and MyVariant.info through the Model Context Protocol.
    Last updated 10 days ago
    35
    366
    MIT License
    • Apple
    • Linux

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