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Open-Source MCP servers

Production-ready MCP servers that extend AI capabilities through file access, database connections, API integrations, and other contextual services.

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12,146 servers. Last updated 2025-12-04 15:11
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  • Noctua MCP Serverofficial

    geneontology
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    Enables editing and querying of Gene Ontology Causal Activity Models (GO-CAMs) through the Barista API. Supports model creation, individual and fact management, evidence addition, and causal pathway construction for biological knowledge representation.
    Last updated a month ago
    18
    BSD 3-Clause

  • medical-mcp

    JamesANZ
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    An MCP server that provides comprehensive medical information by querying multiple authoritative medical APIs including FDA, WHO, PubMed, Google Scholar, and RxNorm.
    Last updated a month ago
    433
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    5
    38
    MIT License
    • Apple

  • BioOntology MCP Server

    Augmented-Nature
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    A production-ready Model Context Protocol (MCP) server that provides comprehensive access to the BioOntology API for searching, annotating, and exploring over 1,200 biological ontologies.
    Last updated 5 months ago
    10
    8
    MIT License

  • Protein MCP Server

    gqy20
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    Enables searching, retrieving, and downloading protein structure data from the RCSB Protein Data Bank. Supports intelligent protein structure search, comprehensive data retrieval, and multiple file format downloads for bioinformatics research.
    Last updated a month ago
    3
    MIT License

  • GeneOntology MCP Server

    Augmented-Nature
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    A comprehensive Model Context Protocol server for accessing Gene Ontology (GO) data, enabling AI systems to perform ontology-based analysis, gene annotation research, and functional enrichment studies.
    Last updated 5 months ago
    4
    0
    7
    MIT License

  • NCBI Gene MCP Server

    mohammadnajeeb
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    MCP server that interfaces with the NCBI Entrez API to fetch detailed information about genes and proteins, enabling gene searches, gene/protein metadata retrieval, and symbol searching with organism filtering.
    Last updated 4 months ago
    4
    3
    MIT License

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