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FHIR MCP Server

by the-momentum

📋 Table of Contents

🔍 About The Project

FHIR MCP Server implements a complete Model Context Protocol (MCP) server, designed to facilitate seamless interaction between LLM-based agents and a FHIR-compliant backend. It provides a standardized interface that enables full CRUD operations on FHIR resources through a comprehensive suite of tools - accessible from MCP-compatible clients such as Claude Desktop, allowing users to query and manipulate clinical data using natural-language prompts.

✨ Key Features

  • 🚀 FastMCP Framework: Built on FastMCP for high-performance MCP server capabilities
  • 🏥 FHIR Resource Management: Full CRUD operations for all major FHIR resources
  • 📄 Intelligent Document Processing: AI-powered document ingestion and chunking for multiple formats including TXT, CSV, JSON, and PDF
  • 🔍 Semantic Search: Advanced document search using vector embeddings (via Pinecone)
  • 🧠 RAG-Ready: Retrieval-Augmented Generation pipeline with context-aware document queries
  • 🔐 Secure Authentication: OAuth2 token management for FHIR API integration
  • 📊 LOINC Integration: Standardized medical terminology lookup and validation
  • 🐳 Container Ready: Docker support for easy deployment and scaling
  • 🔧 Configurable: Extensive .env-based configuration options

🏗️ Architecture

The server is built with a modular architecture:

  • MCP Tools: Dedicated tools for selected FHIR resource types, with others handled by a generic tool
  • Fhir Server Client: Handles FHIR API communication and authentication (OAuth2 and more planned)
  • RAG Services: Embedding-based document processing and semantic retrieval
  • Vector Store: Pinecone integration for similarity-based search
  • LOINC Client: Integration with LOINC API for terminology resolution and validation

💡 Demo

This demo shows how Claude uses the fhir-mcp-server to communicate with a FHIR server (in this case Medplum) to answer questions. You will see, among other things:

  • utilization of the request_patient_resource tool which retrieves basic patient information
  • utilization of the request_condition_resource tool to answer the question whether any of the previously diagnosed diseases may cause symptoms that the patient is currently complaining about
  • utilization of the request_medication_resource, request_encounter_resource, request_generic_resource tools to answer the question whether the patient has already received any treatment for hypertension

You can observe how Claude automatically selects the tools worth using to answer the question based on the user's query.

https://github.com/user-attachments/assets/3a3a8ed3-f881-447d-af03-5f24432a2cdd

Here you can observe how Claude first uses the tool searching for LOINC codes for the lipid panel specific codes, but not finding any related observations in FHIR server, it repeats the search for individual biomarkers that make up such a panel.

https://github.com/user-attachments/assets/2fb39801-d5d6-4461-bedd-9f58ab4d52ec

Developers working with FHIR often need to generate specific test data to validate FHIR server functionality, such as search capabilities and data relationships. While you can use Synthea to generate synthetic data and then manually import the resulting bundles to your server, fhir-mcp-server streamlines this process by allowing you to generate and deploy test data directly through Claude.

This eliminates the typical workflow of running synthea separately, downloading bundles, and manually importing them to your FHIR server. Instead, you can create targeted test scenarios, generate appropriate synthetic data, and populate your server all within Claude's interface.

https://github.com/user-attachments/assets/d87da1d8-6401-4a9e-a6f0-50ba23396e12

Note: fhir-mcp-server was not designed with this use case in mind, so as you'll see in the demo, it doesn't work perfectly - what can be observed, however, is how well the LLM handles using trial and error to correct any wrong choices.

🚀 Getting Started

Follow these steps to set up FHIR MCP Server in your environment.

Prerequisites

  • Docker (recommended) or uv: For dependency management 👉 uv Installation Guide
  • FHIR Server Account: Access to FHIR API (e.g. Medplum)
  • Pinecone API key (required for document search): Enables vector-based search over processed documents. Without it, semantic retrieval features will be unavailable. 👉 Create Pinecone Account
  • LOINC Account (optional): Enables retrieval of the latest LOINC codes from the official API. Without it, the system relies on static or language model-inferred codes, which may be outdated or imprecise. 👉Create LOINC Account

Installation & Setup

  1. Clone the repository:
    git clone https://github.com/the-momentum/fhir-mcp-server cd fhir-mcp-server
  2. Set up environment variables:
    cp config/.env.example config/.env
    Edit the config/.env file with your credentials and configuration. See Environment Variables
  3. Install DependenciesFor Docker-based execution run:
    make build
    For uv-based execution run:
    make uv
  4. Update the MCP Client configuratione.g. Claude Desktop -> edit claude_desktop_config.json
  • Docker
    { "mcpServers": { "docker-mcp-server": { "command": "docker", "args": [ "run", "-i", "--rm", "--init", "--name", "fhir-mcp-server", "--mount", // optional - volume for reload "type=bind,source=<your-project-path>/app,target=/root_project/app", // optional - volume for reload "--mount", "type=bind,source=<your-project-path>/config/.env,target=/root_project/config/.env", "mcp-server:latest" ] } } }
    Make sure to replace <your-project-path> with the actual path to your installation
  • uv Firstly, get uv path from terminal:
    • Windows:
      (Get-Command uv).Path
    • MacOS/Linux:
      which uv

    Then, update config file:

    { "mcpServers": { "uv-mcp-server": { "command": "uv", "args": [ "run", "--frozen", "--directory", "<your-project-path>", "start" ], "env": { "PATH": "<uv-bin-folder-path>" } } } }

    Make sure to replace with the actual uv path (to bin folder)

  1. Restart MCP ClientAfter completing all of the above steps, restart the MCP Client to apply the changes. In some cases, you may need to terminate all related processes using Task Manager or your system's process manager. This ensures that:
    • The updated configuration is properly loaded
    • Environment variables are correctly applied
    • The FHIR MCP client initializes with the correct settings

🔧 Configuration

🔐 Security & Encryption

The FHIR MCP Server includes built-in encryption infrastructure to protect sensitive configuration values. Sensitive fields like API keys and passwords are automatically encrypted and decrypted at runtime.

You are allowed to store passwords as a plain text, but if you want to have them encrypted, follow the instruction below.

Setting Up Encryption

For most users, use the automated setup script:

# uv method uv run scripts/cryptography/setup_encryption.py # docker method docker exec fhir-mcp-server uv run scripts/cryptography/setup_encryption.py

This script will:

  1. Check for MASTER_KEY in config/.env and generate one if needed
  2. Automatically encrypt all sensitive values (LOINC_PASSWORD, FHIR_SERVER_CLIENT_SECRET, PINECONE_API_KEY)
  3. Update your .env file with encrypted values
  4. Skip empty variables and already encrypted values
  1. Generate a Master Key:
    # uv method uv run scripts/cryptography/generate_master_key.py # docker method docker exec fhir-mcp-server uv run scripts/cryptography/generate_master_key.py
    Put that key as a MASTER_KEY environment variable in .env.
  2. Encrypt Sensitive Values:
    # uv method uv run scripts/cryptography/encrypt_setting.py "your_secret_value" # docker method docker exec fhir-mcp-server uv run scripts/cryptography/encrypt_setting.py "your_secret_value"
  3. Decrypt Values (for verification):
    # uv method uv run scripts/cryptography/decrypt_setting.py "encrypted_value" # docker method docker exec fhir-mcp-server uv run scripts/cryptography/decrypt_setting.py "encrypted_value"
Encrypted Configuration Fields

The following fields are automatically encrypted when using EncryptedField:

  • FHIR_SERVER_CLIENT_SECRET - OAuth2 client secret for FHIR server
  • LOINC_PASSWORD - LOINC account password
  • PINECONE_API_KEY - Pinecone API key for vector search
Environment Variables
VariableDescriptionExample ValueEncryption
MASTER_KEYMaster encryption keygAAAAABl...Required
FHIR_SERVER_HOSTFHIR API host URLhttps://api.medplum.comNo
FHIR_BASE_URLFHIR base path/fhir/R4No
FHIR_SERVER_CLIENT_IDOAuth2 client ID for FHIR019720e7...No
FHIR_SERVER_CLIENT_SECRETOAuth2 client secret for FHIRgAAAAABl...Yes
LOINC_ENDPOINTLOINC API search endpointhttps://loinc.regenstrief.org/searchapi/loincsNo
LOINC_USERNAMELOINC account usernameloinc-userNo
LOINC_PASSWORDLOINC account passwordgAAAAABl...Yes
PINECONE_API_KEYPinecone API keygAAAAABl...Yes
EMBEDDING_MODELHugging Face embedding model nameNeuML/pubmedbert-base-embeddingsNo

🛠️ MCP Tools

The FHIR MCP Server provides a comprehensive set of tools for interacting with FHIR resources and document management:

FHIR Resource Tools

ToolResource TypeDescription
request_patient_resourcePatientManage patient demographic and administrative information
request_observation_resourceObservationHandle clinical measurements and assessments
request_condition_resourceConditionManage patient problems and diagnoses
request_medication_resourceMedicationHandle medication information and orders
request_immunization_resourceImmunizationManage vaccination records
request_encounter_resourceEncounterHandle patient visits and interactions
request_allergy_intolerance_resourceAllergyIntoleranceManage patient allergy information
request_family_member_history_resourceFamilyMemberHistoryHandle family health history
request_generic_resourceAny FHIR ResourceOperate on any FHIR resource not covered by specific tools

Document Management Tools

ToolDescription
request_document_reference_resourceManage FHIR DocumentReference resources
add_document_to_pineconeIngests documents into the vector database for semantic search
search_pineconePerforms semantic search across indexed documents using vector embeddings

LOINC Terminology Tools

ToolDescription
get_loinc_codesRetrieves standardized LOINC codes for medical observations and laboratory tests

Tool Features

  • Full Resource Management: All FHIR resource tools support Create, Read, Update, and Delete operations
  • Data Validation: Tools enforce FHIR resource validation and prevent data corruption
  • Error Handling: Comprehensive error responses with detailed failure information
  • Security: OAuth2 authentication and proper access control for all operations
  • Semantic Search: AI-powered document search using vector embeddings
  • Multi-format Support: Document ingestion supports TXT, PDF, CSV, and JSON formats

🗺️ Roadmap

We're continuously enhancing FHIR MCP Server with new capabilities. Here's what's on the horizon:

  • Extended Authentication Options: In addition to OAuth2 (already supported), we plan to add support for other authentication methods for connecting to FHIR servers
  • Expanded File Format Support for RAG: Extend document ingestion capabilities to support additional formats
  • Table-Aware Document Chunking: Improve the document chunking pipeline by detecting tables in documents and treating them as separate, atomic chunks.
  • OCR Support for Scanned Documents: Implement Optical Character Recognition capabilities to enable extraction of text from scanned PDFs and image files before chunking and indexing

Have a suggestion? We'd love to hear from you! Contact us or contribute directly.

👥 Contributors

📄 License

Distributed under the MIT License. See MIT License for more information.


-
security - not tested
A
license - permissive license
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quality - not tested

hybrid server

The server is able to function both locally and remotely, depending on the configuration or use case.

Enables LLM-based agents to interact with FHIR healthcare data through natural language prompts, providing full CRUD operations on FHIR resources, document processing, and semantic search capabilities.

  1. 🔍 About The Project
    1. ✨ Key Features
    2. 🏗️ Architecture
  2. 💡 Demo
    1. 🚀 Getting Started
      1. Prerequisites
      2. Installation & Setup
    2. 🔧 Configuration
      1. 🔐 Security & Encryption
    3. 🛠️ MCP Tools
      1. FHIR Resource Tools
      2. Document Management Tools
      3. LOINC Terminology Tools
      4. Tool Features
    4. 🗺️ Roadmap
      1. 👥 Contributors
        1. 📄 License

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